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pentobarbital will reduce the level or result of fentanyl transdermal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration of fentanyl with CYP3A4 inducers may lead to your reduce in fentanyl plasma concentrations, not enough efficacy or, possibly, growth of a withdrawal syndrome inside of a indiv